This special session will focus on cutting-edge developments in Global Navigation Satellite Systems (GNSS) and their innovative applications on Space, Lunar and beyond. Topics of interest include next-generation interoperable system architecturesfor Space, Lunar PNT and beyond, precise ODTS (Orbit Determination and Timing Synchronisation) techniques, lunar reference frames and timing reference frames, multi-sensor fusion navigation terminals. The session also aims to give an insight in ongoing activities in relevant programs such as ESA LCNS (Lunar Communication and Navigation Service) Moonlight, JAXA Lunar Navigation Satellite System (LNSS), NASA LCRNS (Lunar Communications Relay and Navigation System) or other international initiatives, or space agencies cooperation (LunaNet) to highlight innovations that will enable safer, more efficient exploration missions to the Moon and beyond.